Package: gatekeepR
Title: Reviewable Marker Gating and Phenotyping for Multiplexed Imaging
Version: 1.1.0
Authors@R: 
    person("R.", "Heller",
           email = "raban.heller@uni-ulm.de",
           role = c("aut", "cre", "cph"),
           comment = c(ORCID = "0000-0001-8006-9742"))
Description: Turns per-cell marker measurements from multiplexed tissue
        images into reviewed cell types and state calls. Declares a
        marker panel and an ordered phenotype hierarchy as data,
        decides per image whether each marker can be called at all, and
        estimates thresholds with documented methods (manual, density
        valley, density tail, two-component Gaussian mixture,
        population density crossing on an embedding and parent-specific
        crossing). A single classifier is shared by batch code and the
        review application. Reviewer decisions are kept in append-only
        ledgers, and a review is locked into a content-addressed export
        whose labels, decisions and deletion histories can be replayed
        and verified.
License: MIT + file LICENSE
URL: https://github.com/CTTIR/gatekeepR
BugReports: https://github.com/CTTIR/gatekeepR/issues
Depends: R (>= 4.1.0)
Imports: cli, data.table, digest, fs, filelock, jsonlite, lifecycle,
        MASS, rlang, stats, utils
Suggests: callr, cellspecR (>= 1.0.0), EBImage, dbscan, ggplot2,
        jsonvalidate, knitr, patchwork, pkgload, rmarkdown, shiny,
        testthat (>= 3.0.0), uwot, withr
Additional_repositories: https://cttir.r-universe.dev
Config/testthat/edition: 3
VignetteBuilder: knitr
Encoding: UTF-8
Language: en-US
Roxygen: list(markdown = TRUE)
Config/Needs/website: CTTIR/themakR
Config/roxygen2/version: 8.0.0
Config/pak/sysreqs: cmake make libuv1-dev
Repository: https://cttir.r-universe.dev
Date/Publication: 2026-11-03 11:21:03 UTC
RemoteUrl: https://github.com/CTTIR/gatekeepR
RemoteRef: HEAD
RemoteSha: 4ecea65d4dd5104ef3f6b2b62457977e6191cee6
NeedsCompilation: no
Packaged: 2026-11-03 18:08:30 UTC; root
Author: R. Heller [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0001-8006-9742>)
Maintainer: R. Heller <raban.heller@uni-ulm.de>